Extended Data Fig. 3: INU1-derivatives do not trigger disseminated thrombosis. | Nature Cardiovascular Research

Extended Data Fig. 3: INU1-derivatives do not trigger disseminated thrombosis.

From: Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb/IIIa dependent platelet activation

Extended Data Fig. 3

Cryo-sections of different murine organs (scale 100 µm) taken 20 min after vehicle (control; n = 6), INU1-IgG (0.75 µg/g; n = 6) or INU1-fab (0.5 µg/mL; n = 6) i.v. injection. Thrombi/platelets were visualized using hematoxylin and eosin (a, upper panels - lung) or anti-GPIX, green – counter-stained with anti-CD31, magenta and DAPI, gray; a-d. Representative sections of lung (a), liver (b), kidney (c) and spleen (d).

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