Extended Data Fig. 3: The Piezo1fl/flMCM+/- mice show normal cardiac function and morphology under baseline conditions. | Nature Cardiovascular Research

Extended Data Fig. 3: The Piezo1fl/flMCM+/- mice show normal cardiac function and morphology under baseline conditions.

From: Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice

Extended Data Fig. 3

(a-h) Echocardiographic analysis of (a) HR, heart rate, (b) LVEDV, LV end-diastolic volumes, (c) LVESV, LV end-systolic volumes, (d) LVEF, LV ejection fraction, (e) h, LV wall thickness, (f) r, chamber radius, (g) h/r ratio, LV wall thickness to chamber radius ratio and (h) LV mass, n = 6/group. (i-p) Anatomic analysis of (l) BW, body weight, (j) HW, heart weight, (k) LVW, left ventricular weight, (l) LW, lung weight, (m) HW/BW, heart weight to body weight ratio, (n) LVW/BW, left ventricular weight to body weight ratio, (o) LVW/TL, left ventricular weight to tibia length ratio, (p) LW/BW, lung weight to body weight ratio, n = 7/group. Results are presented as mean ± SEM, one-way ANOVA with Tukey’s post-hoc test for multiple comparisons were used for a-p.

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