Extended Data Fig. 8: Definition of heart model VT circuits.
From: Fat infiltration in the infarcted heart as a paradigm for ventricular arrhythmias
VT circuits were defined using the UVC system. Letting the grey dot (left panel) denote the UVC corresponding to the manually annotated VT exit site, the VT circuit was defined as all tissues falling within 0.2 units (ξ) in terms of the apicobasal axis, 36° or π/5 radians (Ф) for the rotational axis, and the full transmural myocardium (ρ) for these areas. The activation sequence for a given VT circuit (right panel) from one re-entrant cycle to the next was systematically divided into 8 isochrones: exit site (purple), outer loop (grey and red), entrance (orange), the common pathway (yellow, green, cyan, blue), and the critical isthmus (cyan, blue). UVC: universal ventricular coordinates, VT: ventricular tachycardia.
