Extended Data Fig. 4: MAGMA Tissue and Gene Set Enrichment. | Nature Cardiovascular Research

Extended Data Fig. 4: MAGMA Tissue and Gene Set Enrichment.

From: Genetics of varicose veins reveals polygenic architecture and genetic overlap with arterial and venous disease

Extended Data Fig. 4: MAGMA Tissue and Gene Set Enrichment.The alternative text for this image may have been generated using AI.

a) Tissue enrichment was assessed using MAGMA via the online FUMA platform, integrating GWAS summary statistics for varicose veins with gene expression (RNAseq) data from GTEx V8. b) Gene set enrichment results from MAGMA. Tissues (panel A) enriched at a false discovery rate threshold of 5% are noted by red bars. Pathways (panel B) enriched at a Bonferroni-adjusted p < 0.05 points are noted by red dots.

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