Extended Data Fig. 10: Genes implicated in NAD+ synthesis from NAM are repressed in DCM-affected human hearts.
From: KDM8 epigenetically controls cardiac metabolism to prevent initiation of dilated cardiomyopathy
Heatmap of normalized mRNA levels of genes encoding enzymes in the NAD synthesis as per RNA-seq in human healthy control and DCM-affected hearts. Significantly decreased genes are in purple and increased in yellow. Data was analyzed with DESeq2.
