Extended Data Fig. 7: Average expression of genes with similarities to tissue-resident memory (TRM)-like T cells in different CD8 Teff/mem T cells among different tissues. | Nature Cardiovascular Research

Extended Data Fig. 7: Average expression of genes with similarities to tissue-resident memory (TRM)-like T cells in different CD8 Teff/mem T cells among different tissues.

From: Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis

Extended Data Fig. 7: Average expression of genes with similarities to tissue-resident memory (TRM)-like T cells in different CD8 Teff/mem T cells among different tissues.

a, 237 plaque CD8 Teff/mem T cells were grouped into 6 subtypes resulting from tSNE analyses based on their top 2000 highly expressed genes; Dot-plot shows the average expression of genes associated with T cell egression-, activation-, and TRM-like T cell phenotypes; b, 726 ATLO CD8 Teff/mem T cells were grouped into 5 subtypes; c, 2339 Apoe-/- RLNs CD8 Teff/mem T cells were grouped into 6 subtypes; d, 1688 WT RLNs CD8 Teff/mem T cells were grouped into 6 subtypes; CD8 Teff/mem T cells were obtained from three independent experiments. Each dot represents one single cell.

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