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No crops without seeds: the risks in declining support for fundamental research

Nature Cardiovascular Research volume 2, pages 193–195 (2023) Cite this article

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Over recent decades, shifts toward translational or applied research in many countries have come at the expense of fundamental discovery research. Here we discuss the historical importance of basic science in the cardiovascular field, the risks in its decline and the ongoing need for a strong foundation in fundamental discovery research.

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Fig. 1: The Hogan/Smith suburban vegetable patch in Melbourne, Australia.
The alternative text for this image may have been generated using AI.

References

  1. Owens, B. Science Insider https://www.science.org/content/article/canada-scientists-are-struggling-stagnant-funding (2022).

  2. Australian Academy of Science. Science in Australia (2021); https://www.science.org.au/curious/policy-features/science-australia

  3. Mervis, J. Science Insider https://www.science.org/content/article/data-check-us-government-share-basic-research-funding-falls-below-50 (2017).

  4. Collins, F. S. et al. Science 351, 1405 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Landis, S. NINDS Blog https://blog.ninds.nih.gov/2014/03/27/back-to-basics/ (2016).

  6. Brown, M. S. & Goldstein, J. L. Sci. Am. 251, 58–66 (1984).

    Article  CAS  PubMed  Google Scholar 

  7. Stossel, T. P. Cell 134, 903–905 (2008).

    Article  CAS  PubMed  Google Scholar 

  8. Craven, L. L. Ann. West. Med. Surg. 4, 95 (1950).

    CAS  PubMed  Google Scholar 

  9. Hynes, R. O. Matrix Biol. 23, 333–340 (2004).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Coller, B. S. & Shattil, S. J. Blood 112, 3011–3025 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Lander, E. S. Cell 164, 18–28 (2016).

    Article  CAS  PubMed  Google Scholar 

  12. Gillmore, J. D. et al. N. Engl. J. Med. 385, 493–502 (2021).

    Article  CAS  PubMed  Google Scholar 

  13. Frangoul, H. et al. N. Engl. J. Med. 384, 252–260 (2021).

    Article  CAS  PubMed  Google Scholar 

  14. Barrett, P., Hansen, N.-J., Natal, J.-M. & Noureldin, D. IMF Blog https://www.imf.org/en/Blogs/Articles/2021/10/06/blog-ch3-weo-why-basic-science-matters-for-economic-growth (2021).

  15. US National Institutes of Health. Impact of NIH Research—Our society (2018); https://www.nih.gov/about-nih/what-we-do/impact-nih-research/our-society

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Acknowledgements

The authors thank Kelly Smith and Lizzie Mason for thoughtful comments.

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Authors and Affiliations

  1. Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

    Benjamin M. Hogan

  2. Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia

    Benjamin M. Hogan

  3. Department of Anatomy and Physiology, University of Melbourne, Melbourne, Victoria, Australia

    Benjamin M. Hogan

  4. Department of Medicine and Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, USA

    Mark L. Kahn

  5. Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia

    Natasha L. Harvey

  6. Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia

    Natasha L. Harvey

Authors
  1. Benjamin M. Hogan
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  2. Mark L. Kahn
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  3. Natasha L. Harvey
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Corresponding authors

Correspondence to Benjamin M. Hogan, Mark L. Kahn or Natasha L. Harvey.

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The authors declare no competing interests.

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Hogan, B.M., Kahn, M.L. & Harvey, N.L. No crops without seeds: the risks in declining support for fundamental research. Nat Cardiovasc Res 2, 193–195 (2023). https://doi.org/10.1038/s44161-023-00225-x

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