Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Briefing
  • Published:

Distributions of venous sinusoids and lymphatic vessels in the mouse nasal cavity

Our work defines three-dimensional atlases that illustrate the morphological and molecular heterogeneity of the mouse nasal vasculature and lymphatic system. The unique features of these vessels offer insights into their associations with nasal inflammation, infection and aging.

This is a preview of subscription content, access via your institution

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Venous sinuses and lymphatic vessels in the mouse nasal cavity.
The alternative text for this image may have been generated using AI.

References

  1. Harkema, J. R., Carey, S. A. & Wagner, J. G. The nose revisited: a brief review of the comparative structure, function, and toxicologic pathology of the nasal epithelium. Toxicol. Pathol. 34, 252–269 (2006). A comprehensive review of the nasal cavity.

    Article  CAS  PubMed  Google Scholar 

  2. Zuckerkandl, E. Uber den Circulations-Apparat in der Naseschleimhaut. Denkschr. Akad. Wiss. Wien 49, 121–152 (1885). This landmark paper included a hand-drawn 3D color rendering of the nasal blood vessels in humans and sheep.

    Google Scholar 

  3. Petrova, T. V. & Koh, G. Y. Biological functions of lymphatic vessels. Science 369, eaax4063 (2020). A review article that presents organ-specific lymphatic heterogeneities.

    Article  CAS  PubMed  Google Scholar 

  4. Baluk, P. & McDonald, D. M. Buttons and zippers: endothelial junctions in lymphatic vessels. Cold Spring Harb. Perspect. Med. 12, a041178 (2022). A review article that describes characteristics of two types of intercellular junction of lymphatic vessels.

    Article  CAS  PubMed  Google Scholar 

  5. Ahn, J. H. et al. Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19. J. Clin. Invest. 131, e148517 (2021). A review article that provides direct evidence that nasal ciliated cells are primary targets for SARS-CoV-2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This is a summary of: Hong, S. P. et al. Three-dimensional morphologic and molecular atlases of nasal vasculature. Nat. Cardiovas. Res. https://doi.org/10.1038/s44161-023-00257-3 (2023).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Distributions of venous sinusoids and lymphatic vessels in the mouse nasal cavity. Nat Cardiovasc Res 2, 423–424 (2023). https://doi.org/10.1038/s44161-023-00262-6

Download citation

  • Published:

  • Version of record:

  • Issue date:

  • DOI: https://doi.org/10.1038/s44161-023-00262-6

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing