Extended Data Fig. 9: Structural comparisons.
From: Structural insights into human ABCC4-mediated transport of platelet agonist and antagonist
Superposition of dipyridamole-bound ABCC4 (yellow) against a apo-form ABCC4 (gray) and b U46619-bound ABCC4 (gray). c Superposition of the key residues in the dipyridamole-binding pocket against those in the apo-form ABCC4. The interacting residues are shown as sticks and labeled. d Superposition of aspirin-bound ABCC4 (cyan) against dipyridamole-bound ABCC4 (gray).
