Extended Data Fig. 4: Exemplar ECGs from adult zebrafish gene knockouts (KO) and their wildtype (WT) siblings.
From: Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram
Signal-average trace (black) overlaid R-aligned traces from individual beats (green). a) Nrap knockout ECGs displayed repolarization abnormalities such that T-waves were not discernible from signal noise (red underscored period). b) ECGs from inf2 knockout fish had continued rising activity throughout the PR segment without achieving an isoelectric level as typically seen in wildtype or other knockouts (red underscored period). c) ECGs from pde4dip knockout fish displayed greater variance in signal waveform between individual beats showing substantial deviations from mean well in excess of typical noise (extrema envelope in red).
