Extended Data Fig. 4: Secondary monocyte class confirmation markers for annotation.
From: Cell-intrinsic effects of clonal hematopoiesis in heart failure
a-c. Violin plots of common monocyte subclass maker genes for (a) classical monocytes, (b) intermediate monocytes and (c) non-classical monocytes confirming monocyte annotation. d. Heatmap of unbiased monocyte subclass maker regulated genes. e. Number of upregulated genes in DNMT3A mutant cells versus wild type cells in different monocyte classes in pooled analysis. f. Novel DNMT3A-mutant associated gene regulation differentially are called from parent GO term associated with immune processes and inflammation. (CM: classical monocytes; IM: intermediate monocytes; NCM: non-classical monocytes). (Significance denoted by * and reflects adj. p-value < 0.05).
