Extended Data Fig. 8: Tbx5+shYbx1 treatment induced cardiac cells from human fibroblasts. | Nature Cardiovascular Research

Extended Data Fig. 8: Tbx5+shYbx1 treatment induced cardiac cells from human fibroblasts.

From: Translational landscape of direct cardiac reprogramming reveals a role of Ybx1 in repressing cardiac fate acquisition

Extended Data Fig. 8: Tbx5+shYbx1 treatment induced cardiac cells from human fibroblasts.

(a-b) Representative flow plots and quantification data for αActinin+ cells 12 days after reprogramming factor (TBX5) and indicated shRNAs infected hCFs (n = 3 independent experiments). (c) Representative image of hiCMs in TBX5 +shYBX1 cultures. (d) Quantification of cardiac gene expression in indicated groups (n = 3 independent experiments). Statistical significance was calculated using two-tailed t test for paired samples. Error bars indicate means ± SEM.

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