Extended Data Fig. 6: Silencing ARSE expression increases contractile gene expression in human aortic vascular smooth muscle cells. | Nature Cardiovascular Research

Extended Data Fig. 6: Silencing ARSE expression increases contractile gene expression in human aortic vascular smooth muscle cells.

From: Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification

Extended Data Fig. 6: Silencing ARSE expression increases contractile gene expression in human aortic vascular smooth muscle cells.

Silencing ARSE in cells (n = 12 biologically independent samples in each group) grown in normal media increased a) ACTA2 and b) TAGLN (SM22α) mRNA levels by ~ 56% and 35%, respectively. Statistical comparisons were made using a two-tailed Student t test. The mean is depicted in plots, with the error bars representing the standard error of the mean.

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