Extended Data Fig. 6: Reduced hematopoiesis and myocardial myeloid cell content in AdipoqCreERT2Atglfl/fl mice.
From: Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction
a, Bone marrow adipocyte immunofluorescence images stained with perilipin-1 in Atglfl/fl versus AdipoqCreERT2Atglfl/fl mice 3 days after MI. b, Quantification of adipocyte size (n = 4 Atglfl/fl, n = 6 AdipoqCreERT2Atglfl/fl, two-tailed Welch’s t test, three independent experiments). c, Quantification of blood leukocytes in Atglfl/fl controls and AdipoqCreERT2Atglfl/fl mice 3 days after MI (n = 9 Atglfl/fl, n = 8 AdipoqCreERT2Atglfl/fl, two-tailed Welch’s t test, three independent experiments). d, Quantification of bone marrow leukocytes in Atglfl/fl controls and AdipoqCreERT2Atglfl/fl mice 3 days after MI (n = 9 Atglfl/fl, n = 9 AdipoqCreERT2Atglfl/fl, two-tailed Welch’s t test, three independent experiments). e, Flow plots of infiltrated leukocytes in the hearts of Atglfl/fl controls and AdipoqCreERT2Atglfl/fl. f, Quantification of macrophages, monocytes and neutrophils in the myocardium of Atglfl/fl controls and AdipoqCreERT2Atglfl/fl mice 3 days after MI (n = 9 Atglfl/fl, n = 9 AdipoqCreERT2Atglfl/fl, two-tailed Welch’s t test, three independent experiments). Data are displayed as mean ± SEM.
