Extended Data Fig. 5: Genetically downregulated IL-6 signaling via perturbation in IL6 is associated with lower risk of atherosclerotic cardiovascular disease in UK Biobank.
From: IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk
Data are presented as hazard ratios per 24%-decrease in CRP; error bars correspond to 95% confidence intervals. Pvalues for coronary artery disease, peripheral artery disease, and ischemic stroke were: p = 0.03, p = 0.009, and p = 0.44, respectively. All reported p-values are two-sided. Abbreviations: IL-6, interleukin-6; CRP, C-reactive protein; CI, confidence interval; HR, hazard ratio.
