The lymphatic vasculature has emerged as a key component of the heart’s response to injury, influencing both regeneration and maladaptive remodeling. Research now highlights the role of lymphatic clearance in shaping the composition of tissue-resident macrophages within the neonatal heart.
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Acknowledgements
The van Rooij lab is supported by funding from the European Union’s Horizon 2020 research and innovation program under grant agreement no. 874764.
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Koopmans, T., van Rooij, E. Maintaining the LYVE1 line through macrophage and lymphatic interplay in the regenerating neonatal heart. Nat Cardiovasc Res 4, 1211–1213 (2025). https://doi.org/10.1038/s44161-025-00707-0
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DOI: https://doi.org/10.1038/s44161-025-00707-0
