Fig. 2: Spatiotemporal cell type dynamics of the immune compartments.
From: Spatiotemporal dynamics of the cardioimmune niche during lesion repair
a, UMAP of scRNA-seq data of immune populations from day 1–56 post-lesion. Color code of cell types is also indicated in c. b, DEGs for each immune population. Dot size indicates fraction of cells expressing the gene. Dot color indicates normalized expression level. c, Immune cell type proportions across days 1–56 and sham. d,e, Spatial maps of immune cells for sham, day 7 and day 28 (d), with quantification of myeloid/lymphoid cell frequencies across IZ/FZ, BZ and RZ for day 7 and day 28 samples under the detailed annotation scheme (e). Spatial maps of individual cell types are shown (d, bottom). Arrows point to the IZ area. f, Spatial distribution of different mo/MP subtypes in the wound regions (or the edge of LV for sham). Dotted lines separate IZ/FZ and BZ.
