Fig. 3: Spatiotemporal cell type dynamics of the fibroblast compartments.
From: Spatiotemporal dynamics of the cardioimmune niche during lesion repair
a, UMAP of scRNA-seq data for FB subtypes from day 1–56 post-lesion. Color code of cell types is indicated in c. b, DEGs for each FB subtype, grouped into ‘Quiescent’, ‘Early’, ‘myoFB’ and ‘matFB’ states. Dot size indicates fraction of cells expressing the gene. Dot color indicates normalized expression level. c, Cell type proportion of FB subtypes across days 1–56 and sham. d, Annotated spatial map showing distribution of FB subtypes in day 7 and 28 hearts. e, Quantification of FB cell state frequencies across IZ/FZ, BZ and RZ for day 7 and 28 samples. f, Spatial maps showing distribution of individual FB subtypes in the wound regions of day 7 and 28 hearts.
