Extended Data Fig. 3: Conditional haploinsufficiency of Tbx5 in the interventricular septum (IVS) leads to ventricular septal defects (VSDs). | Nature Cardiovascular Research

Extended Data Fig. 3: Conditional haploinsufficiency of Tbx5 in the interventricular septum (IVS) leads to ventricular septal defects (VSDs).

From: A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects

Extended Data Fig. 3: Conditional haploinsufficiency of Tbx5 in the interventricular septum (IVS) leads to ventricular septal defects (VSDs).

a–c, At E14.5, membranous VSDs were observed in Mef2cAHF-Cre;ROSA26mTmG/+;Tbx5flox/+ mutant embryos (n = 4/7) compared to Mef2cAHF-Cre;ROSA26mTmG/+;Tbx5+/+ controls (n = 0/3). Right ventricle (RV), left ventricle (LV) and interventricular septum (IVS). All scale bars equal 200 microns.

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