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Translating Nobel Prize-winning Treg cell science into cardiovascular therapy

Nature Cardiovascular Research volume 5, pages 1–3 (2026)Cite this article

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The 2025 Nobel Prize in Physiology or Medicine honored a scientific breakthrough with hidden cardiovascular potential: regulatory T cells and peripheral immune tolerance. These mechanisms provide a paradigm shift for understanding and treating cardiovascular disease, dampening inflammation without compromising immunity, and offering safer and more effective therapies.

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Acknowledgements

This work is supported by the British Heart Foundation (RCZE/029, CH/10/001/27642).

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Authors and Affiliations

  1. Section of CardioRespiratory Medicine, Department of Medicine, University of Cambridge, Cambridge, UK

    Ziad Mallat

  2. INSERM U970, Université Paris Cité, Paris, France

    Ziad Mallat

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  1. Ziad Mallat
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Correspondence to Ziad Mallat.

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Mallat, Z. Translating Nobel Prize-winning Treg cell science into cardiovascular therapy. Nat Cardiovasc Res 5, 1–3 (2026). https://doi.org/10.1038/s44161-025-00765-4

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