Extended Data Fig. 5: Clustering analysis of T cell subpopulations.

a, Uniform Manifold Approximation and Projection (UMAP) analysis of T cells, including naive CD4⁺ T cells, naive CD8⁺ T cells, and effector memory CD4⁺ T cells. Naive CD4⁺ T cells were identified as CD3E⁺, CD4⁺, CCR7^high, TCF7^high, SELL^high, CD69^low, FAS⁻, IL7R⁺ T cells. Naive CD8⁺ T cells were identified as CD3E⁺, CD8A⁺, CCR7^high, TCF7^high, SELL^high, CD69^low, FAS⁻, IL7R⁺ T cells. Effector memory CD4⁺ T cells were identified as CD3E⁺, CD4⁺, CCR7^low, TCF7^low, SELL^low, CD69^high, FAS⁺, IL7R⁺ T cells. b, Cell-type gene markers for each cluster, with the percentage of expressing cells and the average expression level used to identify cell types.