Fig. 6: In situ imaging of mouse aorta with flexible microendoscope. | Communications Engineering

Fig. 6: In situ imaging of mouse aorta with flexible microendoscope.

From: Liquid-shaped microlens for scalable production of ultrahigh-resolution optical coherence tomography microendoscope

Fig. 6

a A flexible microendoscope is deployed from the left femoral artery to the aortic arch in the mouse. b Cut-way view of a reconstructed 3D OCT image of a 14.6-mm-long mouse descending thoracic aorta. c Representative OCT cross section indicated with a green dashed box in (b). d, e 3x close-up view of the region boxed with red dashed lines in (c) and its correlated hematoxylin and eosin (H&E) histology. The white arrow points to the deep tissue. f, g Example quantification of each fine tissue layer’s thickness (distance between red dashed lines) of mouse aorta along an A-line depth (the white arrow in d) (f). The thickness and its standard deviation of each aorta layer were measured using 40 A-lines from 10 representative OCT cross-sections (g). TI tunica intima, TM tunica media, TA tunica adventitia, EL elastic lamellae, AT adipose tissue. Scale bars are 100 μm.

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