Fig. 1: Opportunities and barriers to innovate at the interface of engineering and maternal-fetal medicine.

Opportunities include cost reduction and increased accessibility approaches such as implementing advanced models and existing drug technologies with regulatory approvals to accelerate therapeutic development. Barriers to innovation include social stigmas, funding, regulatory attitudes towards maternal-fetal health, restricted healthcare access, and biological limitations with pregnant animal models, all of which make translation challenging. Created in BioRender. Howlett, T. (2026) https://BioRender.com/1zfdvrs.