Table 2 Significant clusters from whole-brain analysis of food-cue reactivity comparing high and low discrimination groups

From: Discrimination exposure impacts unhealthy processing of food cues: crosstalk between the brain and gut

Contrast high > low discrimination

Cluster region(s)

X (MNI)

Y (MNI)

Z (MNI)

Maximum Z

Unhealthy sweet food versus nonfood

L insula

−26

20

−6

3.70

L insula

−24

26

10

3.67

L inferior frontal gyrus, pars opercularis

−42

18

10

3.63

L lateral orbitofrontal cortex

−26

22

-2

3.51

L inferior frontal gyrus, pars opercularis

−32

16

24

3.35

Frontal operculum

−34

14

16

3.35

Unhealthy savory food versus nonfood

R orbitofrontal cortex

20

34

−12

3.94

R orbitofrontal cortex

22

38

−12

3.93

R frontal pole

22

38

−18

3.75

R putamen

22

20

2

3.61

R caudate

14

22

−4

3.52

R insular

26

26

2

3.32

Healthy food versus nonfood

R middle frontal gyrus (dlPFC)

24

28

34

4.08

R superior frontal gyrus (vmPFC)

22

64

24

3.89

R middle frontal gyrus (dlPFC)

36

8

40

3.86

R superior frontal gyrus (dlPFC)

20

18

54

3.82

Frontal pole (dlPFC)

28

44

36

3.64

R middle frontal gyrus (dlPFC)

24

32

40

3.58

Unhealthy sweet food versus healthy sweet food

vmPFC

24

56

28

3.65

Unhealthy savory food versus healthy savory food

Not significant

    
  1. Family-wise error cluster level correction: Z > 2.3, P < 0.05. Peak voxel coordinates are in MNI space. Results were controlled for BMI, sex, age, race, diet and SES. High discrimination, n = 50; low discrimination, n = 57.
  2. L, left hemisphere; R, right hemisphere.