Extended Data Fig. 1: Statistical difference in the classifier-identified discriminative FCs between CUD patients and healthy controls, examined by two-sample t-tests.

a, All significant hyperconnections (CUD > healthy controls). b, All significant hypoconnections (CUD < healthy controls). Histogram indicated the node strength calculated from the sum of the linked FC importance. VIS, visual network; SMN, somatomotor network; DAN, dorsal attention network; VAN, ventral attention network; LIM, limbic network; FPC, frontoparietal control network; DMN, default mode network. Only the significant t values that survived FDR were shown.