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Diffuse glioma location is associated with extremes of depressive symptoms

Mood dysfunction is more common in people with brain tumors than in those with other tumor types, but the reasons for this association are unclear. Using various methods for lesion–symptom mapping, we identified brain locations in patients with diffuse glioma that are related to severe depressive symptoms or an absence of depressive symptoms.

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Fig. 1: Brain regions in which tumors are associated with depressive symptoms.

References

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This is a summary of: van Genderen, M. N. G. et al. Tumor location is associated with mood dysfunction in patients with diffuse glioma. Nat. Ment. Health https://doi.org/10.1038/s44220-024-00275-5 (2024).

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Diffuse glioma location is associated with extremes of depressive symptoms. Nat. Mental Health 2, 747–748 (2024). https://doi.org/10.1038/s44220-024-00276-4

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