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Mapping connectivity and network alterations in youth depression by functional brain imaging

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Analyses of functional MRI brain images of young people with depression revealed that altered brain connectivity associated with this disorder is circumscribed to specific networks and hub regions, including the default mode and attentional networks. The magnitude of these connectivity changes is a reliable predictor of depression symptom severity.

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Fig. 1: Brain circuits associated with youth depression.

References

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This is a summary of: Tse, N. Y. et al. A mega-analysis of functional connectivity and network abnormalities in youth depression. Nat. Ment. Health https://doi.org/10.1038/s44220-024-00309-y (2024).

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Mapping connectivity and network alterations in youth depression by functional brain imaging. Nat. Mental Health 2, 1138–1139 (2024). https://doi.org/10.1038/s44220-024-00327-w

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