Fig. 1: Association between genetic risk for schizophrenia and retinal thickness. | Nature Mental Health

Fig. 1: Association between genetic risk for schizophrenia and retinal thickness.

From: Genetic susceptibility to schizophrenia through neuroinflammatory pathways associated with retinal thinness

Fig. 1: Association between genetic risk for schizophrenia and retinal thickness.

a, The anatomy of the eye and retina, displayed as a cross section of the eye, and a macular section of the retina. Optical coherence tomography measurements divide the macula into nine subfields, as indicated by the white crosshairs. The macular thickness is measured in micrometers. The structure of the different layers of the inner and outer retina is displayed on the right. b,c, The association between polygenic risk scores (z-scored) for schizophrenia and overall mean macular thickness (in micrometers) (b) and outer retinal thickness (c) averaged across both eyes. Solid lines represent the regression estimates, while complementary shaded areas correspond to the 95% confidence intervals. INLRPE, inner nuclear layer to the retinal pigment epithelium. Panel a was created with BioRender.com.

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