Table 2 Basic demographic1, exposure and outcome variables in full analytical sample, stratified by ancestry and year

From: Polygenic score for C-reactive protein is linked to faster cortical thinning and psychopathology risk in adolescents

EU sample (sample 1)

Year 0 (n = 6,336)

Year 2 (n = 4,617)

Mean cortical thickness (mean (s.d.)2)

2.74 (0.08)

2.70 (0.08)

Depression (mean (s.d.))

53.60 (5.66)

53.94 (6.02)

Internalizing (mean (s.d.))

48.70 (10.45)

48.30 (10.33)

Externalizing (mean (s.d.))

45.42 (10.01)

44.47 (9.65)

Polygenic score for CRP (mean (s.d.))

−0.18 (0.93)

−0.18 (0.93)

Age (years)

9.92 (0.63)

11.96 (0.65)

Sex at birth, female (%)

2,982 (47.1%)

2,080 (45.1%)

Body mass index (mean (s.d.))

17.92 (3.31)

19.69 (4.01)

Non-EU sample (sample 2)

Year 0 (n=4,878)

Year 2 (n=3,206)

Mean cortical thickness (mean (s.d.))

2.70 (0.08)

2.66 (0.08)

Depression (mean (s.d.))

53.61 (5.80)

53.55 (5.83)

Internalizing (mean (s.d.))

48.19 (10.91)

46.96 (10.76)

Externalizing (mean (s.d.))

46.26 (10.74)

44.81 (10.18)

Polygenic score for CRP (mean (s.d.))

0.25 (1.04)

0.24 (1.03)

Age (years)

9.90 (0.62)

11.94 (0.66)

Sex at birth, female (%)

2,347 (48.1%)

1,511 (47.1%)

Body mass index (mean (s.d.))

19.78 (4.46)

21.66 (4.80)

Full meta-analysis sample

Year 0 (n=11,214)

Year 2 (n=7,823)

Mean cortical thickness (mean (s.d.))

2.72 (0.08)

2.69 (0.08)

Depression (mean (s.d.))

53.60 (5.72)

53.78 (5.95)

Internalizing (mean (s.d.))

48.48 (10.66)

47.75 (10.53)

Externalizing (mean (s.d.))

45.77 (10.34)

44.63 (9.87)

Polygenic score for CRP (mean (s.d.))

0.00 (1.00)

−0.01 (1.00)

Early-life infection, yes (%)

1,710 (16.7%)

1,218 (16.9%)

Age (years)

9.91 (0.63)

11.95 (0.65)

Sex at birth, female (%)

5,329 (47.5%)

3,591 (45.9%)

Body mass index (mean (s.d.))

18.73 (3.96)

20.49 (4.45)

  1. 1Owing to page limitations, detailed socioeconomic variables (race/ethnicity, parental education and household income) are presented in Supplementary Table 14.
  2. 2s.d., standard deviation.