Fig. 2: Early onset preeclampsia disease signature. | npj Women's Health

Fig. 2: Early onset preeclampsia disease signature.

From: Transcriptomic comparison of early onset preeclampsia and placenta accreta identifies inverse trophoblast and decidua functions at the maternal-fetal interface

Fig. 2: Early onset preeclampsia disease signature.

a Heat map depicting differential gene expression by case (early onset preeclampsia) and control (preterm control) of the 4 merged microarray studies at an adjusted p-value of <0.05. Analysis demonstrated 2600 differentially expressed genes, of which 1239 are upregulated and 1361 are downregulated. The color gradient legend represents normalized gene counts. b Volcano plot of differential gene expression for early onset preeclampsia, with genes labeled in blue for an adjusted p-value of <0.05 and red for both an adjusted p-value of <0.05 and a log2FC difference of 0.5. NS indicates non-significant.

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