Table 2 Comparative analysis of early onset preeclampsia merged dataset compared to single-cell placenta accreta differential gene expression, by cell type

From: Transcriptomic comparison of early onset preeclampsia and placenta accreta identifies inverse trophoblast and decidua functions at the maternal-fetal interface

Placenta

cell type

# Accreta differentially expressed genes

# Overlap genes with early onset preeclampsia

Hyper

enrichment

p-value

Correlation coefficient r

Correlation

p-value

Decidua 1

410

103

3.04 × 10−7*

−0.38

7.11 × 10−5*

Decidua 2

25

10

0.003*

−0.49

0.150

Decidua 3

2180

417

1.12 × 10−6*

−0.13

8.00 × 10−3*

Endothelial

3282

710

5.58 × 10−25*

−0.18

9.20 × 10−7*

Cytotrophoblast

51

20

3.88 × 10−5*

−0.42

0.060

Syncytiotrophoblast

1343

278

1.28 × 10−7*

−0.01

0.840

Extravillous trophoblast

1713

411

6.17 × 10−22*

−0.16

0.002*

Lymphoid

31

13

4.00 × 10−4*

−0.42

0.160

Myeloid

222

50

4.00 × 10−4*

−0.15

0.290

  1. Cell type rows with both significant gene set hyper enrichment and negative correlation are bolded.
  2. *p < 0.05.
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