Fig. 3: Immunohistochemistry for MERS-CoV antigen in respiratory tract of mice inoculated via the intranasal route or via aerosols. | npj Viruses

Fig. 3: Immunohistochemistry for MERS-CoV antigen in respiratory tract of mice inoculated via the intranasal route or via aerosols.

From: Transmission dynamics of MERS-CoV in a transgenic human DPP4 mouse model

Fig. 3: Immunohistochemistry for MERS-CoV antigen in respiratory tract of mice inoculated via the intranasal route or via aerosols.

a, b Nasal turbinates; (c, d) Trachea; (e, f) Lungs; (a, c, e) Intranasal inoculation; (b, d, f) Aerosol inoculation. Tissues were stained with an in-house produced rabbit polyclonal antiserum against HCoV-EMC/2012 for the detection of viral antigen. Immunohistochemistry staining reveals MERS-CoV antigen in type I and type II pneumocytes and limited staining in nasal turbinates (image represents only staining found). Inserts highlight affected cells. Nasal turbinates (200x), trachea (200x) and lung tissue (100 and 400x insert) are shown.

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