Fig. 4: Transmission of MERS-CoV via fomites.
From: Transmission dynamics of MERS-CoV in a transgenic human DPP4 mouse model
hDPP4 mice were exposed to 5 × 104 TCID50 MERS-CoV (N = 18) or 5 × 106 TCID50 MERS-CoV (N = 20). a Survival curves of hDPP4 mice exposed to fomites containing MERS-CoV. Viral gRNA (b) or sgRNA (c) in lung and brain tissue of hDPP4 mice that reached endpoint criteria. d Infectious MERS-CoV detected in lung and brain tissue of hDPP4 mice that reached endpoint criteria. e Serology titers in sera of survivors obtained 28 dpe. ELISA assays were performed using MERS-CoV S1 protein. Dotted line = limit of detection. ** = p < 0.01.
