Fig. 1: Emergence of the giant cell phenotype following irradiation of A549 cells. | npj Imaging

Fig. 1: Emergence of the giant cell phenotype following irradiation of A549 cells.

From: Increased [18F]FDG uptake of radiation-induced giant cells: a single-cell study in lung cancer models

Fig. 1

a Graph showing percentage of giant cells and average diameter of A549 cells, as a function of the radiation dose received. The cells were characterized 3 days after irradiation. b Representative brightfield images of unirradiated and irradiated A549 cells, 4 days after 12 Gy irradiation (scale bar, 220 µm). c Flow cytometry data showing giant and non-giant populations for both unirradiated and irradiated (12 Gy) A549 cells. d Increase in cell size of both unirradiated and 12 Gy irradiated A549 cells over time (****P < 0.0001).

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