Fig. 3: Radiation induced giant cells have increased [18F]FDG uptake. | npj Imaging

Fig. 3: Radiation induced giant cells have increased [18F]FDG uptake.

From: Increased [18F]FDG uptake of radiation-induced giant cells: a single-cell study in lung cancer models

Fig. 3

a Single-cell [18F]FDG uptake measured by gamma counting after single-cell dispensing. Data was acquired 5 days after irradiation (12 Gy) of A549 cells (****p < 0.0001). b Same experiment, was performed using H1299 cells irradiated with 6 Gy (****p < 0.0001). c The data in a, plotted to highlight the correlation between forward scattering (FSC) representing size, side scattering (SSC) representing granularity, and [18F]FDG uptake. The diameter of the solid bubbles represents [18F]FDG uptake in Bq of single cells. d Radioluminescence microscopy imaging of non-giant (unirradiated) and giant cells (12 Gy irradiated). Sections of the image are magnified to depict the radioluminescence in individual cells.

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