Fig. 5: Histological comparison of viable and senescent cell implants in pig knee cartilage.
From: MRI detection of senescent cells in porcine knee joints with a β-galactosidase responsive Gd-chelate
After MRI, the pig knee joints were excised and processed for histology. Fluorescence images of cartilage defects with implants of senescent cells and viable control cells, stained with (A) p16 (×2 magnification), (B) p21 (×2 magnification), and (C) β-gal (×2 magnification). D Fluorescence intensity of senescent cells and viable controls on respective stains. All data are displayed as mean data and standard deviations of eight implants per group. *p < 0.05.
