Fig. 4: In vivo magnetic resonance imaging with Fe-PyC3A corroborates reactive oxygen species-related oxidative tissue changes identified by immunohistochemistry.

a–d Representative post-contrast magnetic resonance images at dt for spleens (a), bone marrows (b), livers (c), and kidneys (d), and graphs showing the time points of the magnetic resonance imaging (MRI) readout over the course of the experiment. e Correlation matrices between imaging and immunohistochemistry (IHC) readouts. * indicates statistically significant comparisons (p < 0.05). 4-HNE 4-hydroxy-2-nonenal; MPO myeloperoxidase; non-exp non-exposed; 3 dpe 3 d post-exposure; dt day terminal.