Fig. 5: The spillover effect on fiducial signals during dynamic in vivo MPI.
From: Spillover can limit accurate signal quantification in MPI
Top panels present the experimental setup and MPI scans of fiducials F1 and F2 placed at positions P1-P7 near the liver/spleen (L/S), a with no mouse and b–d post intravenous sequential injection of b the first 20 µg, c the second 20 µg, and finally d the additional 40 µg iron. Images were obtained 40 min after each injection. Bar graphs represent quantification of signal intensity for each fiducial, showing how the spillover effect impacts the accuracy of signal measurement as a function of the proximity of fiducials to a tissue of interest. Error bars represent the SD of the mean signal intensity, measured in pixels within the ROIs.
