Table 1 Baseline characteristics
Characteristics | Overall (n = 845) | Non-MAFLD (n = 568) | MAFLD (n = 277) | P value |
|---|---|---|---|---|
Age, years | 49.10 (40.56–59.62) | 45.21 (34.6–57.35) | 57.84 (48.02–62.31) | <0.0001 |
Men, n (%) | 300 (35.50) | 166 (29.23) | 134 (48.38) | <0.0001 |
Education, n (%) | <0.0001 | |||
Illiteracy/primary school | 45 (5.33) | 24 (4.23) | 21 (7.58) | |
Junior high school | 430 (50.89) | 255 (44.89) | 175 (63.18) | |
College or higher | 370 (43.79) | 289 (50.88) | 81 (29.24) | |
Active physical activity, n (%) | 477 (56.45) | 300 (52.82) | 177 (63.90) | 0.0095 |
Current smoking, n (%) | 159 (18.82) | 85 (14.96) | 74 (26.71) | <0.0001 |
Current drinking, n (%) | 132 (15.62) | 79 (13.91) | 53 (19.13) | 0.0495 |
Hypertension, n (%) | 104 (12.31) | 34 (5.99) | 70 (25.27) | <0.0001 |
Diabetes, n (%) | 36 (4.26) | 10 (1.76) | 26 (9.39) | <0.0001 |
Dyslipidemia, n (%) | 54 (6.39) | 12 (2.11) | 42 (15.16) | <0.0001 |
Antihypertensive agents, n (%) | 88 (10.41) | 26 (4.58) | 62 (22.38) | <0.0001 |
Antidiabetic agents, n (%) | 31 (3.67) | 10 (1.76) | 21 (7.58) | <0.0001 |
Lipid-lowering agents, n (%) | 13 (1.54) | 4 (0.70) | 9 (3.25) | 0.0048 |
Body mass index, kg/m2 | 23.40 (21.40–25.70) | 22.23 (20.4–23.76) | 26.30 (24.44–28.60) | <0.0001 |
Systolic blood pressure, mmHg | 120.00 (111.00–130.00) | 116.00 (107.00–125.00) | 129.00 (119.50–143.00) | <0.0001 |
Diastolic blood pressure, mmHg | 76.00 (69.00–84.00) | 73.00 (68.00–81.00) | 82.00 (75.00–89.00) | <0.0001 |
Fasting blood glucose, mmol/L | 5.00 (4.70–5.40) | 4.90 (4.70–5.20) | 5.30 (4.90–5.90) | <0.0001 |
Total cholesterol, mmol/L | 4.39 ± 0.81 | 4.26 ± 0.72 | 4.66 ± 0.91 | <0.0001 |
Triglyceride, mmol/L | 1.00 (0.73–1.37) | 0.90 (0.68–1.16) | 1.36 (0.97–1.77) | <0.0001 |
LDL cholesterol, mmol/L | 2.35 (2.01–2.78) | 2.26 (1.95–2.64) | 2.62 (2.23–3.09) | <0.0001 |
HDL cholesterol, mmol/L | 1.23 (1.08–1.44) | 1.31 (1.14–1.49) | 1.12 (0.99–1.27) | <0.0001 |
Triglyceride-glucose index | 8.29 (7.97–8.66) | 8.18 (7.87–8.46) | 8.69 (8.31–9.08) | <0.0001 |
eGFR, ml/min/1.73 m2 | 92.92 ± 15.27 | 94.92 ± 15.71 | 88.82 ± 13.44 | <0.0001 |
Serum uric acid, μmol/L | 261.75 (214.90–317.00) | 243.15 (201.60–293.60) | 304.20 (251.85–359.30) | <0.0001 |
Alanine transaminase, U/L | 15.90 (11.90–22.60) | 14.10 (11.10–19.40) | 20.00 (15.30–27.00) | <0.0001 |
Aspartate aminotransferase, U/L | 20.00 (18.00–24.00) | 20.00 (17.00–23.00) | 21.00 (18.00–26.00) | <0.0001 |
γ-Glutamyl Transferase, U/L | 16.30 (12.00–23.00) | 14.35 (11.10–19.10) | 21.50 (16.10–32.80) | <0.0001 |