Table 2 Association between MAFLD with the trajectories of MMSE (large decrease pattern as the outcome of interest)

From: Longitudinal association of metabolic dysfunction-associated fatty liver disease, serum metabolites, with cognitive function trajectories

Models

Non-MAFLD (n = 568)

MAFLD (n = 277)

P value

Cases, n (%)

59 (10.39)

72 (25.99)

 

Model 1

Reference

3.03(2.07–4.43)

<0.0001

Model 2

Reference

1.83(1.21–2.77)

0.0044

Model 3

Reference

1.84(1.20–2.81)

0.0048

Model 4

Reference

1.81(1.16–2.84)

0.0090

  1. MAFLD metabolic dysfunction-associated fatty liver disease.
  2. Model 1: unadjusted.
  3. Model 2: adjusted for age and sex.
  4. Model 3: further adjusted for body mass index, education, physical activity, smoking, and drinking.
  5. Model 4: further adjusted for hypertension, dyslipidemia, estimated glomerular filtration rate, and alanine transaminase.
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