Fig. 2: Characteristics of clinical variables among diagnostic groups by mean BMD.
From: Metagenomic analysis revealing links between age, gut microbiota and bone loss in Chinese adults
a Heatmap shows partial Spearman’s correlations between clinical variables (Methods). Red color denotes positive association, blue denotes negative association. The size of squares indicates the absolute Spearman’s rho. Stars, BH-adjusted P < 0.001. b Scatter plot shows the associations between the mean BMD and age in overall (n = 684), women (n = 330) and men (n = 354). Spearman’s rho values and P values are shown. The center line represents the median value, boxes denote the interquartile ranges (IQRs) between the first and third quartiles, and whiskers extend 1.5 times the IQR from the top and bottom of the box. c Box plot shows the differences of age, BMI and WHR among normal control (NC), osteopenia (ON) and osteoporosis (OP) groups (n = 684). d Percentage of current smoking status, averaged intake of alcohol per week, dairy products, and red meat consumption in diagnostic groups. e Bar plot shows the percentage of sex in diagnostic groups. f Box plot shows the sex-difference of mean BMD in each diagnostic group. ANCOVA analyses are performed to determine the significance in (c, f) after adjusting for other covariances (Method). Pearson’s Chi-squared tests are conducted to assess the distribution of categorical variables in (d, e).
