Table 1 Characteristics in normal control (NC), osteopenia (ON) and osteoporosis (OP) groups (n = 684)
From: Metagenomic analysis revealing links between age, gut microbiota and bone loss in Chinese adults
Variables | Total (n = 684) | Normal control (NC, n = 194) | Osteopenia (ON, n = 344) | Osteoporosis (OP, n = 146) | P-valuea | P-valueb | ||
|---|---|---|---|---|---|---|---|---|
OP vs. NC | ON vs. NC | OP vs. ON | ||||||
Bone mass density (BMD, mg/cm3) | ||||||||
L1-BMD | 109.7 (31.18) | 145.37 (19.18) | 106.65 (14.34) | 69.16 (15.54) | 5.77 × 10−114 | 6.19 × 10−124 | 8.75 × 10−100 | 1.78 × 10−93 |
L2-BMD | 103.15 (30.20) | 138.58 (18.82) | 99.54 (13.05) | 64.26 (13.49) | 5.09 × 10−118 | 8.13 × 10−129 | 1.37 × 10−107 | 4.94 × 10−100 |
L3-BMD | 99.86 (30.92) | 135.54 (18.73) | 96.60 (14.83) | 60.08 (14.31) | 1.30 × 10−114 | 1.26 × 10−127 | 1.92 × 10−100 | 4.73 × 10−91 |
Mean BMD | 104.17 (29.67) | 139.78 (16.56) | 100.91 (11.72) | 64.55 (12.39) | 2.40 × 10−125 | 3.37 × 10−144 | 1.97 × 10−125 | 3.28 × 10−118 |
Demographics and anthropometrics | ||||||||
Age, years | 58.72 (6.18) | 55.71 (4.98) | 58.22 (5.24) | 63.91 (6.47) | 5.24 × 10−31 | 4.96 × 10−32 | 5.36 × 10−08 | 6.70 × 10−23 |
Sex (Female %), No | 330 (48.25%) | 76 (39.18%) | 161 (46.80%) | 93 (63.70%) | 3.29 × 10−05 | 1.26 × 10−05 | 0.11 | 8.85 × 10−4 |
Body mass index, kg/m2 | 25.36 (3.34) | 25.65 (3.33) | 25.24 (3.22) | 25.24 (3.62) | 0.28 | / | / | / |
Waist-hip ratio | 0.88 (0.07) | 0.88 (0.07) | 0.88 (0.07) | 0.88 (0.07) | 0.39 | / | / | / |
