Fig. 4: Cellular composition of mouse liver analyzed by snRNA-Seq on the 10X Chromium platform (10X Genomics).

A Combined UMAP plot of transcriptional profiles of single nuclei from Run21%, Run13%, Sed21%, and Sed13% livers. All identified hepatocytes (Hep) and non-parenchymal cells, including Kupfer cells (KC), hepatic stellate cells (HSC), endothelial cells (Endo), cholangiocytes (Chol), and immune cells (Imm) are shown. B–G Expression of cluster marker genes specific for the major cell types in the liver. Hamp, hepatocytes; Clec4, Kupffer cells; Reln, Stellate cells; Clec4g, Endothelial cells; Btla, B cells; Nrc1, NK cells.