Cardiovascular diseases (CVDs) remain the leading cause of mortality and morbidity, underscoring the urgent need for innovative research and transformative clinical solutions. The field of cardiovascular health encompasses a vast spectrum of scientific inquiry and clinical practice—from molecular mechanisms to population-level interventions, from risk factor exploration to the management of end-stage clinical events. Historically, cardiovascular research has been segmented into basic, clinical, and epidemiological disciplines. Yet, as these domains rapidly evolve, there is a growing need for a unified platform to disseminate paradigm-shifting discoveries that bridge gaps and improve outcomes. To meet this critical need, we launched npj Cardiovascular Health in March 2024. As a Nature Partner Journal, we are dedicated to publishing high-impact, interdisciplinary research spanning the full continuum of cardiovascular science—from bench to bedside and beyond.

Since the launch of npj Cardiovascular Health, the journal has served as an open-access forum for rigorously peer-reviewed, pioneering work that reflects the diversity of the field. Our published original research addresses pressing clinical questions in CVD diagnosis, treatment, prognosis, and etiology. For instance, AI-driven approaches leveraging multimodal or multi-omics data have advanced clinical screening, diagnosis, and prediction1,2,3,4. A translational framework was also developed for genoproteomic studies for cardiovascular drug discovery5. In therapeutics, an observational study was conducted to investigate the relationship between proton pump inhibitors and the risk of gastrointestinal bleeding in oral anticoagulant users6, while a pragmatic clinical trial evaluated the efficacy of obesity treatments in primary care settings7. Prognostic insights have emerged from studies identifying risk factors for cardiovascular outcomes associated with COVID-19 and linking gut microbiota metabolism to poor outcomes8,9,10. Additionally, novel risk factors for coronary artery disease, heart failure, atrial fibrillation, valvular heart diseases, and aortic stenosis have been elucidated11,12,13,14,15. These contributions underscore our commitment to unraveling the causes, prevention, and management of CVDs through clinically relevant innovation. Beyond original research, we have curated reviews synthesizing advancements across a broad range of conditions, including acute coronary syndrome, chronic coronary disease, heart failure, stroke, atrial fibrillation, atrial cardiomyopathy, and acute aortic dissection16,17,18,19,20,21,22,23,24,25,26. These articles reflect the latest scientific progress and diverse perspectives shaping cardiovascular health today.

To accelerate collaboration, we have launched nine thematic Collections, uniting researchers across disciplines to tackle specific challenges. npj Cardiovascular Health actively promotes dialogue across specialties, as seen in our collection —“Digital Health Technologies: An Evolving Paradigm in the Transformation of Cardiovascular Care”. We also prioritize studies addressing unmet needs in the collections, such as women’s cardiovascular health across the lifespan and the pursuit of novel therapeutic targets.

As an open-access journal, we ensure that knowledge reaches clinicians, researchers, and policymakers without barriers. Our editorial team, led by experts in cardiology, translational medicine, and epidemiology, is committed to a fair and rigorous review process that upholds the highest standards of scientific integrity. Looking ahead, npj Cardiovascular Health aspires to be a catalyst for progress in a field that impacts millions of lives worldwide. We invite submissions that challenge conventions, leverage cross-disciplinary collaborations, and advance equity in cardiovascular care. It is an honor to serve as the founding Editor-in-Chief of this journal. I look forward to working together with a global community dedicated to a brighter future for cardiovascular health.