Fig. 2: Biosensor specificity for four viral nucleoproteins (Influenza A/B, RSV, and SARS-CoV-2). | npj Biosensing

Fig. 2: Biosensor specificity for four viral nucleoproteins (Influenza A/B, RSV, and SARS-CoV-2).

From: Disposable Point of Care multiplexed plasmonic biosensor for rapid and specific identification of respiratory viruses

Fig. 2

Effect of the buffer composition (PBST and PBST-DS). A Biosensor signal response for the four distinct viral NP (each one at a concentration of 2.50 µg/mL) employing PBST as running conditioning buffer. B Biosensor signal response for the four distinct viral NP (each one at a concentration of 2.50 µg/mL) employing PBST-DS as running buffer. In all cases, the nucleoprotein solutions were prepared in PBST buffer and injected individually across the four biofunctionalized channels (CH1 – CH4), each coated with an antibody specific to one viral NP. The position of each antibody is as follows: CH1 – anti-IBV; CH2 – anti-RSV; CH3 – anti-IAV, and CH4 – anti-COV. Each column represents the mean ± SD of biosensor responses from duplicate measurements. Signals indistinguishable from background levels are marked with an asterisk (*), indicating no detectable response in those channels.

Back to article page