Table 1 Biosensor assay performance for the different viral NPs in standard buffer and diluted nasopharyngeal swabs

From: Disposable Point of Care multiplexed plasmonic biosensor for rapid and specific identification of respiratory viruses

Nucleoprotein

Standard buffer conditions*

Nasopharyngeal swab**

LOD (ng/mL)

Linear range (ng/mL)

R2

LOD (ng/mL)

Linear range (ng/mL)

R2

Influenza B

31.43

150 – 2500

0.98

32.03

150–2500

0.99

RSV A

30.63

150 – 2500

0.97

12.03

150–1000

0.90

RSV B

19.95

150 – 2500

0.96

13.68

150–2500

0.99

Influenza A

118.18

150 – 5000

0.99

148.93

150–5000

0.97

SARS-CoV-2

10.60

150 – 1000

0.91

6.90

150–1000

0.95

  1. *PBST as dilution buffer; PBST-DS as running conditioning buffer.
  2. **Nasopharyngeal swab:lysis buffer (1:1).