Fig. 1: Design and integration of CAMEOs with brain organoids. | npj Biosensing

Fig. 1: Design and integration of CAMEOs with brain organoids.

From: Carbon nanotube microelectrode arrays enable scalable and accessible electrophysiological recordings of cerebral organoids

Fig. 1: Design and integration of CAMEOs with brain organoids.

a Exploded schematic of the 2D cartwheel design, highlighting the constituent layers and transformation into a 3D CAMEO. b Photograph of a fabricated cartwheel with magnified view of the central region showing 12 independent SWCNT microelectrodes (outlined in red), alongside a fully assembled CAMEO. c Complete platform with CAMEOs suspended from a standard 6-well plate lid. d Enlarged top-view of a suspended CAMEO, showing contact pads routed through a transparent flexible printed circuit board. e Photograph illustrating organoid loading via pipetting through an opening on the plate lid. f Image showing all CAMEOs conformally wrapped around organoids in a 6 well platform. g Close-up view of a single CAMEO conformally wrapped around an organoid, with microelectrodes visible on the organoid surface. Scale bars, 1 cm unless otherwise indicated.

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