Fig. 3: Measures of gut physiology across different age groups in IBS. | npj Gut and Liver

Fig. 3: Measures of gut physiology across different age groups in IBS.

From: Distinct age-related characteristics in patients with irritable bowel syndrome: patient reported outcomes and measures of gut physiology

Fig. 3

Rectal sensitivity, including first sensation, urge to defecate, discomfort, and pain thresholds assessed by rectal barostat procedures combined into Z-scores (A), resting anal sphincter pressure (B) and maximum anal squeeze pressure (C) measured by anorectal manometry, and lactulose/mannitol ratio measured during small bowel permeability testing (D), across different age groups in IBS. Rectal sensitivity: 18–29 years; n = 315, 30–49 years; n = 193, ≥50 years; n = 115. Anorectal manometry: 18–29 years; n = 68, 30–49 years; n = 86, ≥50 years; n = 33. Small bowel permeability: 18–29 years; n = 49, 30–49 years; n = 61, ≥50 years; n = 26. Data are presented as mean with 5th and 95th percentiles. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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