Fig. 4: High-dose proton pump inhibitors increase circulating lymphocyte and monocyte subsets in FD. | npj Gut and Liver

Fig. 4: High-dose proton pump inhibitors increase circulating lymphocyte and monocyte subsets in FD.

From: Limited duodenal immune activation in functional dyspepsia is not linked to spinal sensory neuron activation

Fig. 4

Quantification of circulating (A) effector memory (TEM, CD45RA- CD197-) T helper (TH) cells, (B) TEM re-expressing CD45RA (TEMRA, CD45RA+ CD197-) TH cells, (C) gut-homing (α4β7+) T cells, (D) small-intestinal directed (α4β7+ CCR9+) T cells, (E) total monocytes (CD14+), and (F) non-classical monocytes (CD14dim CD16+) was performed using spectral flow cytometry on cryopreserved peripheral blood mononuclear cells. G Circulating total eosinophils (CD193+ CD16-), H as well as the proportion of gut-homing (α4β7+) eosinophils were quantified using flow cytometry on cryopreserved peripheral blood polynuclear cells. Graphs depict mean ± standard deviation with data points corresponding to individual participants.

Back to article page