Table 2 Unadjusted Outcomes in Overall Cohort and Subgroups

From: Trajectory of compensated metabolic dysfunction-associated steatohepatitis in a tertiary center with a large hispanic/latino population

 

Overall (n = 493)

Hispanic/Latino (n = 167)

Not Hispanic or Not Latino (n = 326)

Parameter

Number of events (%)

Annual Incidencea

5-year Incidence

Number of Events (%)

Annual Incidence

5-year Incidence

Number of Events (%)

Annual Incidence

5-year Incidence

Ascites

69 (14.0%)

3.3%

16% [13–21]

31 (18.6%)

5.2%

25% [18–35]

38 (11.7%)

3.0%

12% [8–17]

Esophageal varices hemorrhage

22 (4.5%)

1.0%

4% [3–8]

7 (4.2%)

1.1%

5% [2–15]

15 (4.6%)

1.1%

4% [2–8]

Spontaneous bacterial peritonitis

4 (0.8%)

0.20%

1% [0 - 3]

2 (1.2%)

0.3%

1% [0 - 5]

2 (0.6%)

0.15%

1% [0–4]

Hepatic Encephalopathy

52 (10.6%)

2.5%

13% [10–18]

23 (13.8%)

3.9%

19% [13–28]

29 (8.9%)

2.3%

10% [7–15]

Hepatocellular Carcinoma

24 (4.9%)

1.1%

7% [5–11]

7 (4.2%)

1.1%

6% [3–14]

17 (5.2%)

1.3%

8% [5–13]

Liver transplant

17 (3.5%)

0.80%

6% [3–9]

9 (5.4%)

1.4%

10% [5–20]

8 (2.5%)

0.59%

4% [2–8]

MELD-3 score ≥ 15

48 (9.7%)

2.3%

12% [9–16]

27 (16.2%)

4.6%

19% [14–28]

21 (6.4%)

1.6%

8% [5–12]

eCPT Score ≥ 7

81 (16.4%)

4.1%

19% [15–24]

37 (22.2%)

6.5%

27% [20–36]

44 (13.5%)

3.6%

15% [11–20]

Decompensation symptomsb

98 (19.9%)

5.0%

24% [20–29]

38 (22.8%)

6.8%

31% [23–41]

60 (18.4%)

5.0%

20% [16–26]

Composite outcomec

160 (32.5%)

9.6%

38% [33–43]

62 (37.1%)

11.7%

46% [37–55]

98 (30.1%)

8.8%

34% [28–40]

All-cause Mortality

70 (14.2%)

3.4%

16% [12–20]

31 (18.6%)

4.6%

22% [16–31]

39 (12.0%)

2.8%

12% [9–17]

  1. aCalculated as the number of events divided by the person year of follow-up.
  2. bDefined as the earliest occurrence of any of the following: Ascites, Esophageal varices hemorrhage, SBP, Encephalopathy.
  3. cDefined as the earliest occurrence of any follow-up outcome (Decompensation symptoms, Hepatocellular Carcinoma Liver transplant, MELD-3 ≥ 15, eCPT ≥ 7).